Build your infusion nursing knowledge, strengthen clinical judgment, and prepare for the CRNI® examination.
Infusion Foundations is a comprehensive, 20-hour online course for registered nurses seeking a stronger foundation in infusion therapy and focused preparation for the Certified Registered Nurse Infusion (CRNI®) examination.
Through structured lessons, clinical scenarios, infusion calculations, and original practice questions, you will explore the assessment, technology, and treatment principles essential to safe infusion nursing practice. The course emphasizes patient-specific decisions, recognition of complications, and application of knowledge across acute care, outpatient, home infusion, and long-term care settings.
The curriculum follows the three major domains identified in the INCC CRNI® examination content outline referenced in the January 2026 examination handbook: Principles of Practice, Access Devices, and Infusion Therapies.
Who Should Take This Course?
This course is designed for registered nurses who:
- Are preparing for the CRNI® certification examination.
- Provide or coordinate infusion therapy in hospital, ambulatory, home care, or long-term care settings.
- Want to strengthen their knowledge of vascular access, infusion medications, and complication management.
- Work in nursing education, administration, or other roles involving infusion therapy.
Learners should have a foundation in nursing assessment, pharmacology, and dosage calculations.
What You Will Learn
By the end of this course, you will be better prepared to:
- Apply vascular anatomy and patient assessment findings to access planning.
- Use infection prevention principles during insertion, access, and ongoing device care.
- Plan safe blood sampling and therapeutic phlebotomy.
- Evaluate vascular access devices, infusion equipment, and administration systems.
- Adapt infusion care to pediatric patients, older adults, patients with renal disease, and other populations.
- Recognize infiltration, extravasation, occlusion, and other access complications.
- Interpret fluid, electrolyte, and nutrition findings to evaluate treatment and patient response.
- Apply safe administration and monitoring principles to medications, parenteral nutrition, biologics, and blood products.
- Identify therapy-related reactions and prioritize assessment, intervention, and escalation.
- Solve infusion calculations and approach certification-style questions using clinical reasoning.
Course Content
Module 1: Principles of Infusion Practice and Vascular Anatomy
Professional responsibilities, patient assessment, vascular anatomy and physiology, access planning, and procedural positioning.
Module 2: Infection Prevention and Control
Aseptic practice, skin antisepsis, device care, infection surveillance, bloodstream infection assessment, and prevention strategies.
Module 3: Blood Sampling and Therapeutic Phlebotomy
Specimen collection, blood cultures, access-device sampling, specimen integrity, and therapeutic phlebotomy monitoring.
Module 4: Access Devices and Infusion Technology
Peripheral and central access devices, alternate access, infusion pumps, administration sets, filters, placement technology, securement, and calculations.
Module 5: Access Maintenance and Special Populations
Routine assessment, patency, flushing and locking principles, individualized care, patient education, and transitions between care settings.
Module 6: Access Device Complications
Infiltration, extravasation, catheter occlusion, dislodgement, thrombosis, catheter damage, and other access safety concerns.
Module 7: Fluid and Electrolyte Therapy
Volume assessment, fluid selection, electrolyte disturbances, acid-base concepts, replacement safety, and monitoring.
Module 8: Parenteral Nutrition
Indications, solution components, administration requirements, metabolic monitoring, complications, and transitions in nutrition support.
Module 9: Anti-Infective, Cardiovascular, and Pain Therapies
Medication administration, compatibility, monitoring, outpatient antimicrobial therapy, cardiovascular infusions, and patient-controlled analgesia.
Module 10: Antineoplastics, Biologics, and Blood Products
Treatment verification, vesicant precautions, infusion reactions, transfusion safety, and patient education.
Module 11: Therapy Complications and Integrated Exam Reasoning
Rate-related reactions, hypersensitivity, emergency priorities, hazardous drug precautions, and certification-style clinical reasoning.
Learning Format
The course is designed for self-paced online learning and combines instructional lessons with guided cases, worked calculations, and practice questions with explanations. A diagnostic pretest helps identify areas for review, while module activities reinforce understanding and application.
Course duration: 20 instructional hours. The diagnostic pretest, final assessment, course evaluation, and optional examination practice require additional time.
Presented by: Network4Learning, Inc.
Certification Information
This is an independent educational and examination preparation course. Completion does not establish eligibility for the CRNI® examination, award CRNI® certification, or guarantee examination success. Candidates must independently meet INCC’s current eligibility requirements.
The course does not confer INCC or INS endorsement, CRNI® recertification units, or hands-on procedural competency. CRNI® is a registered trademark of the Infusion Nurses Certification Corporation (INCC). This course is independently developed and presented by Network4Learning, Inc., and is not affiliated with, endorsed by, or approved by INCC. Use of the CRNI® trademark identifies the certification examination for which this course offers preparation.
Strengthen your foundation in infusion nursing and take the next step toward your professional learning goals.